Basic and Translational Science

M. Amin Arnaout Structure and function of integrins in the kidney Mahmoud Nasr Heterotrimeric G protein signaling in kidney diseases Johannes Van Agthoven Structural biology and antagonist design of Integrin

Anna Greka Podocyte biology and targeted therapeutics Sanja Sever Podocyte structure and function, the large regulatory GTPase dynamin Ryuji Morizane Modeling glomerular disease in vascularized kidney organoids derived from human pluripotent stem cells

Jodie Babitt Crosstalk between iron, anemia, inflammation and CKD-MBD Harald Jueppner Calcium and phosphate regulation Petra Simic Kidney-bone interaction

Sahir Kalim Protein and metabolite alterations in uremia Eugene Rhee Kidney metabolism in health and disease

Joseph Bonventre Study of the effects of AKI on the development and progression of kidney fibrosis Li-Li Hsiao Mechanisms of CKD-related cardiovascular complications especially distant tissue fibrosis Ryuji Morizane Modeling Kidney Fibrosis in Kidney Organoids derived from Human Pluripotent Stem Cells

Jamil Azzi Development of liquid biopsy for patients with kidney disease using urinary exosomes Joseph Bonventre Core Laboratory to measure biomarkers of kidney function and injury Eugene Rhee Metabolomic and proteomic markers of kidney disease Leonardo Riella Point-of-Care urine assay using CRISPR/cas13 to monitor transplant patients Venkata Sabbisetti Discovery and validation of biomarkers using omic technologies, identification of novel therapeutic targets in kidney disease Ryuji Morizane Vascularized kidney organoids on chip for efficacy and toxicity testing of somatic genome editing

Jodie Babitt Molecular regulation and therapeutics for iron homeostasis disorders

Dennis Brown Acid-base transport by proton pumps in collecting duct intercalated cells Jenny Lu Mechanism of the trafficking of a water channel protein, AQP2 David Mount Molecular physiology of uric acid transport

Joseph Bonventre Role of proximal tubule in the pathophysiology of diabetic nephropathy Ryuji Morizane Modeling Diabetic Kidney Fibrosis with Kidney Organoids derived from Human Pluripotent Stem Cells

Jodie Babitt Endothelial cell biology in hepatorenal syndrome Joseph Bonventre Mechanisms of AKI and AKI to CKD transition with discovery of new therapeutics Creation of kidney cell populations to create a wearable artificial kidney M. Amin Arnaout Role of integrins in ischemia-reperfusion injury models Ryuji Morizane Recreating Kidney Organogenesis in vitro with Human Pluripotent Stem Cells