FAQs

Transplantation

2020-07-15T19:17:10+00:00

Clinical Training: Care for transplant patients through transplant continuity clinic Participate in donor evaluation clinics Observe living and deceased donor surgeries and gain experience in organ procurement Rotate through tissue typing and histocompatibility laboratories Perform transplant biopsies under ultrasound guidance and review pathology findings with world-renowned pathologists Rotate through vasculitis and glomerulonephritis clinics to gain further experience with immunosuppression management Pursue formal transplant fellowship through AST-accredited transplant nephrology fellowships at both BWH and MGH Scholarly Opportunities: Participate in a wide range of clinical research projects in transplantation Teach and develop curricula for teaching immunology and transplant medicine

Transplantation2020-07-15T19:17:10+00:00

Clinical Trials

2020-07-13T21:13:23+00:00

Anil Chandraker Clinical trials in transplantation Anna Greka Abatacept in Treatment Resistant Nephrotic Syndrome Gearoid McMahon ASCEND: Trial of prolyl hydroxylase inhibitors in patients with CKD and ESRD John Niles Avacopan in C3GN; MAINTANCAVAS: Maintenance treatment in ANCA vasculitis Nina Tolkoff-Rubin Eculizumab for recurrent aHUS post transplant Leonardo Riella Novel drug targets and dietary interventions to promote immune regulation in humans Ajay Singh ASCEND Clinical development program - a phase 3 program for the development of a novel propyl hydroxylase inhibitor Daprodustat. Meghan Sise Clinical trials in Hepatitis C virus infection and HCV+ to HCV-naive kidney transplantation

Clinical Trials2020-07-13T21:13:23+00:00

AKI and ICU Nephrology

2020-07-13T20:59:10+00:00

Andrew Allegretti Hepatorenal Syndrome, AKI in cirrhosis Joseph Bonventre Mechanisms of AKI and AKI to CKD transition with discovery of new therapeutics Kenneth Christopher Critical Care Metabolomics Peter Czarnecki CRRT and volume management in critical illness, COVID and AKI Shruti Gupta Outcomes of COVID-19 in critically ill patients David Leaf Identifying novel risk factors and mechanisms of AKI, and therapies for its prevention and treatment Mallika Mendu Implementation of a standarized algorithim related to RRT initiation and catheter placement (AKI SCAMP)

AKI and ICU Nephrology2020-07-13T20:59:10+00:00

CKD and Dialysis

2020-07-20T16:25:38+00:00

Anemia and Iron in CKD Finnian McCausland Trajectory of hemoglobin changes during CKD, risk factors for anemia, and the association of hemoglobin with outcomes Ajay Singh Development of new anemia treatments in patients with kidney disease Cardiovascular Disease in CKD Finnian McCausland Cardio-renal interactions and risk factors for heart failure and CKD progression - observational studies and interventional trials Dialysis Sahir Kalim Protein carbamylation, amino acid balance, and uremic toxins in CKD Finnian McCausland Modifiable risk factors for intra-dialytic hypotension and cardiovascular disease in hemodiaysis - observational studies and interventional trials Geriatric Nephrology and Palliative Care Sahir Kalim Chronic pain and [...]

CKD and Dialysis2020-07-20T16:25:38+00:00

Renal Physiology and Ion Channels

2020-07-13T20:50:37+00:00

Dennis Brown Acid-base transport by proton pumps in collecting duct intercalated cells Jenny Lu Mechanism of the trafficking of a water channel protein, AQP2 David Mount Molecular physiology of uric acid transport

Renal Physiology and Ion Channels2020-07-13T20:50:37+00:00

Diabetic Nephropathy

2020-07-13T20:05:07+00:00

Joseph Bonventre Role of proximal tubule in the pathophysiology of diabetic nephropathy Ryuji Morizane Modeling Diabetic Kidney Fibrosis with Kidney Organoids derived from Human Pluripotent Stem Cells

Diabetic Nephropathy2020-07-13T20:05:07+00:00

AKI and Kidney Regenerative Medicine

2020-07-24T13:36:05+00:00

Jodie Babitt Endothelial cell biology in hepatorenal syndrome Joseph Bonventre Mechanisms of AKI and AKI to CKD transition with discovery of new therapeutics Creation of kidney cell populations to create a wearable artificial kidney M. Amin Arnaout Role of integrins in ischemia-reperfusion injury models Ryuji Morizane Recreating Kidney Organogenesis in vitro with Human Pluripotent Stem Cells

AKI and Kidney Regenerative Medicine2020-07-24T13:36:05+00:00

Genetics, Genomics, and PKD

2020-07-27T14:03:16+00:00

M. Amin Arnaout Mechanisms of cyst formation in Autosomal Dominant Polycystic Kidney Disease Peter Czarnecki Biochemical mechanisms of intracellular signal transduction that give rise to PKD/other cystic genetic disease Anna Greka Genetics and genomics of kidney diseases Ryuji Morizane CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells. David Mount Translational genomics of hyperuricemia Matt Sampson Kidney disease genomic discovery using population-based, multiomics strategies Jing Zhou Using multidisciplinary approaches including human molecular genetics, developmental biology and mouse genetics to understand the physiology and pathophysiology of polycystins and PKD

Genetics, Genomics, and PKD2020-07-27T14:03:16+00:00

Immunology

2020-07-27T14:04:16+00:00

Autoimmune Renal Disease Anna Greka Podocyte biology and targeted therapeutics Vicki Kelley Innate and adaptive immune mechanisms driving inflammation Angela Schmider Studying the assembly and architecture of the leukotriene synthetic complex in myeloid cells Roy Soberman Signal integration and macromolecular organization in cells of the immune system  Transplant Reza Abdi Targeting Delivery of Immunosuppressive Drugs in Transplantation using Nanotechnology Building a Novel Imaging platform to Detect Graft rejection M. Amin Arnaout Role of integrins in delayed graft function Jamil Azzi Toward targeted therapies in auto and allo-immunity: Immune regulation and beyond Leonardo Riella Mechanisms and Targets of Immune Regulation in Transplantation: [...]

Immunology2020-07-27T14:04:16+00:00

Membrane Biology

2020-07-13T20:43:42+00:00

Sylvie Breton Regulation of epithelial cells in the urogenital tract Dennis Brown Vasopressin action - intracellular trafficking pathways of aquaporin 2 water channels Susan Cheung Signaling pathways modulating aquaporin 2 trafficking and expression affecting water balance disorder Mahmoud Nasr Studying the initial events that lead to viral infection at the molecular level

Membrane Biology2020-07-13T20:43:42+00:00
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